Flumioxazin Considerations

No single herbicide is appropriate for controlling all invasive aquatic plants (or nuisance growths of native aquatic plants), in all situations. A herbicide may perform differently depending on the waterbody, its use, the time of year—or even the time of day. Therefore, aquatic plant managers must have a thorough understanding of how each herbicide acts in Florida aquatic systems. The following parameters are evaluated when considering this herbicide to manage aquatic plants in a specific waterbody. Each parameter is linked to an explanation and examples are provided to demonstrate their relevance to developing comprehensive aquatic plant management strategies.

Table A:  Herbicide Use Patterns for Flumioxazin

Target Plant Scientific Name Use Pattern Compatible Herbicides
Hydrilla Hydrilla verticillata Occasional Use with diquat
Cabomba Cabomba caroliniana Occasional flumioxazin
Water lettuce Pistia stratiotes Frequent flumioxazin
Hygrophila Hygrophila polysperma Frequent flumioxazin
Ludwigia Ludwigia grandiflora Frequent Use with glyphosate
Torpedograss Panicum repens Occasional Use with glyphosate

Table B:  Water Uses and Functions

Water Use Parameters Management Considerations
Downstream Uses and Needs
  • Do not apply in flowing waters
  • Contact type herbicide with short half life – downstream uses minor concern
Fish and Wildlife Mgmt.  
Vegetation planting Avoid contact and potential damage to adjacent susceptible plants – especially water lilies within application zone
Forage and prey No issues related to this tool
  • Moderately toxic to fish – LC50 (96-hour) of 2.3 mg/L in rainbow trout and 21 mg/L in bluegill sunfish
  • Daphnia magna LC50 for 6 mg/L
Non-game wildlife No issues related to this tool
Endangered species No issues related to this tool
Waterfowl Non-toxic to waterfowl – mallard duck > 2,250 mg/kg
Flood Control No issues related to this tool
Navigation and Access No issues related to this tool
Irrigation Do not use treated water for at least 5 days following application
Livestock Consumption There are no restrictions on livestock consumption of treated water
Potable Water No potable water use restrictions
Boating No issues related to this tool
Fishing No fish consumption restriction
Hunting No issues related to this tool
Swimming No swimming restriction

Table C:  Herbicide, Waterbody, Plant, and Climate Parameters

Herbicide Parameters Management Considerations
Herbicide Rate
  • Apply approximately 200 ppb + 0.37 ppm diquat with weighted hoses to control hydrilla – see considerations for diquat if used to control hydrilla
  • Apply approximately 200 ppb to control cabomba
  • Apply ~ 50 ppb for water lettuce control – submersed application
  • Apply 2-8 oz / ac for water lettuce control – foliar application
  • Apply 4 oz / ac + 7.5 pt / ac glyphosate for ludwigia and torpedograss control
Breakdown / Inactivation Short half-life in water depending on season, water depth and especially pH
Microbial Microbial metabolism is  primary degradation pathway in soil – half life ~45 days

Does not bind in sediments or adsorb to soil particles


Susceptible to photodegradation with a half life of 3.2 days

  • Primary degradation pathway in water
  • Half-life of four days at pH = 5 and minutes at pH = 9.0 in laboratory tests
Dissipation Dissipation is minimal with the very short half life
Solid Water dispersible granular herbicide – mix with water and apply as liquid solution
Mode of Action
  • Inhibits protoporphyrinogen oxidase enzyme important in chlorophyll synthesis
  • Cell wall disruptor
Plant Growth Regulator Not used as a plant growth regulator in Florida aquatic plant control applications
Herbicide resistance
  • No tolerance or resistance issues for flumioxazin reported in Florida
  • Resistance has been reported for PPO inhibitors – use rotational and active ingredient combination resistance management strategies where appropriate
Waterbody Parameters  Management Considerations
Water depth Important to know water depth to calculate appropriate concentration
Water volume Important to have accurate bathymetry to calculate appropriate concentration
Water movement Do not apply to flowing water
Water chemistry  
Dissolved oxygen (DO)
  • Relatively fast-acting contact type herbicide
  • Controlling large area may reduce dissolved oxygen level
  • Wait 10-14 days if treating as much as half of the waterbody
pH, alkalinity, hardness
  • pH dependant in field tests
    • Half-life for low pH (6.0-6.2) = 39 hours, medium pH (7.0-7.2) = 18.6 h, high pH (>8.5) = 1.7 hr
    • Use buffer if tank mix water exceeds pH 7.0
    • Apply early in morning when pH is generally at lower values
Nutrient content
No issues related to this tool
Water transparency Higher light intensity usually equates to more robust growth and therefore better control of young submersed target plants (hydrilla / cabomba)
Sediment characteristics  
  • Sand/Clay – no issues related to this tool
  • Organic – no issues related to this tool
Potential for resuspension Does not bind in sediments or adsorb to suspended material in tank mix water
Plant Physiology Parameters  Management Considerations
Plant origin/ growth potential  
Native Use to control cabomba at about 200 ppb
Non-native May be used to control dense growths of water lilies
  • Hydrilla control at about 200 ppb + 0.37 ppm diquat
  • Hygrophila and limnophila control at about 200 ppb
  • Ludwigia grandiflora and torpedograss control at 4 oz / ac + 7.5 pt / ac glyphosate
  • Increasing use for selective water lettuce control
    • ~50 ppb for submersed applications and 2-8 oz / ac foliar application
    • 4 oz / ac + 4 oz / ac penoxsulam for water lettuce / water hyacinth mix
Plant growth stage (target/non-target)
  • Need actively growing plants for herbicide uptake
  • Mature plants more difficult to control due to higher carbohydrate reserves
Plant susceptibility (target/non-target)
  • For best hydrilla control, apply in early fall (October/November) or late winter (February/March) – lower biomass and pH likely lower
  • Water lilies in application zone may be impacted, especially when applied with diquat for hydrilla control
Potential for regrowth (target/non-target) Regrowth is rapid when applied to mature or slowly growing hydrilla
Climate Parameters  Management Considerations
  • Daily
    • Needs 4-8 hours of contact for good herbicidal activity
  • Seasonally
    • Need actively growing target plants for herbicide uptake
Light intensity Higher light intensity usually equates to stronger growth and therefore better control of young submersed plants (hydrilla / cabomba)
Water temperature No issues related to this tool

Table D: Other Parameters

Parameter Management Considerations
Cost No generics available
Anticipated Control Amount  
  • Area of control is generally confined to the area to which flumioxazin is directly applied to target submersed
  • Apply at low dose with expectations of dispersal to control water lettuce
  • Hydrilla efficacy improves when applying to young actively growing plants
  • Better efficacy during cooler weather – October/November – February/March
Time to Achieve Control
  • Floating plants
    • Needs 1-2 hours of foliar contact for control activity
    • Symptoms in 3-5 days – control in 7-14 days
  • Submersed plants
    • Needs 4-6 hours for good control activity
    • Symptoms in 7-14 days – control in 14-28 days
  • Foliar applications by backpack, airboat for small-scale applications to water lettuce
  • Apply with deep water trailing hoses for larger scale submersed plant control